From the Ampere Magnetic Resonance List
The Solid State NMR group in Nijmegen (Kentgens) is searching for a PhD:
Supercritical chromatography hyphenated with hyperpolarized NMR
In our group we develop methods for high sensitivity on-chip NMR detection of mass-limited samples. This flow system allows flexible operation, including high pressures and supercritical solvents such as CO2. The main goal of the project is to develop and optimize a hyphenated setup combining supercritical chromatography with DNP-NMR to provide a fast analytical tool to study complex mixtures with superior information content. One of the advantages of supercritical solvents is the fact that fast mobility can lead to efficient liquid state (Overhauser) Dynamic Nuclear Polarization at relatively high magnetic fields. At present a Gyrotron mm-wave source operating at 395 GHz is available for this purpose, coupled to a 600 MHz NMR spectrometer and a 263 GHz EIO coupled to a 400 MHz NMR spectrometer to be developed further in this project.
The candidate has a MSc in Chemistry of Physics or a related discipline.
We are looking for an enthusiastic candidate with a solid background in NMR and with an affinity for ‘out of the box’ methodology development.
The solid-state NMR group at Radboud University is part of the Institute for Materials and Molecules. The motto ‘From Molecules to Materials’ illustrates our focus on the design, synthesis and characterization of novel functional systems.
The general mission of the solid-state NMR group is to develop new methodology to optimize sensitivity and information content of NMR spectra and to apply these methods to target specific topics in functional molecular systems in terms of local structure and dynamics addressing structure/function relationships. We offer a stimulating and exciting international research environment with state of the art NMR spectrometers.
The advertised position is funded through NWO via the Top institute COAST (www.ti-coast.com). The COAST R&D program’s overall objective is to advance research, development and technical innovation in analytical science for the benefit of its application areas and science as a whole. In this project two academic groups and three industrial partners cooperate; the combination of academic groups specialising in NMR methodology developments (RU Nijmegen), separation methodology (UvA), and Bruker and Waters who are the dominating technology providers in the respective NMR and SFC fields, together with Shell as a potential end user of the technology makes a strong consortium to come up with a viable SFC-NMR approach.
Marian de With
Radboud University | Institute for Molecules and Materials
Secretary for depts. of Biophysical Chemistry and Solid State NMR
Tel. +31 24 3652678
Heyendaalseweg 135 | 6525 AJ Nijmegen | HG03.344
Postbox 9010 | Internal postbus 84 | 6500 GL Nijmegen
Working hours: Monday 9-13, Thursday 9-13, Tuesday, Wednesday and Friday 9-17
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