Category Archives: Postdoc Position

[NMR] Junior postdoctoral position in Barcelona: Optically Detected Magnetic Resonance

Apply at http://jobs.icfo.eu/index.php?detail=485

The Institute of Photonic Sciences (ICFO) in Barcelona, Spain, invites applications for a Junior postdoctoral position in the area of optically detected magnetic resonance.

The successful candidate(s) will join the Atomic Quantum Optics group to carry out research tasks associated with the development of new techniques in atomic physics, magnetometry and magnetic resonance. The candidate will design new magneto-optical sensing approaches that involve atomic and nuclear spin systems. 

Relevant ongoing projects in the group include: 

Development of microfabricated optically pumped atomic magnetometers operating at the femtotesla sensitivity level, for application in biomagnetic field detection. Part of the EU Quantum Flagship program. 

Nuclear magnetic resonance spectroscopy in the ultralow-field regime below earth\’s magnetic field. Supported by EU Marie Skłodowska Curie Actions.

Techniques for atomic and nuclear spin polarization in the ultralow-field regime. Supported by EU Regional Development Fund.

Requirements and conditions

Applicants should hold an internationally recognized Ph.D. degree in Physics, Chemistry or closely related field to experimental quantum optics or magnetic resonance.

Experience in the design, development and implementation of hardware, as well as a knowledge of spin dynamics is essential. 

The applicant should have a demonstrated ability to work with collaborators.

ICFO is an equal opportunity employer. Candidates are selected exclusively on merit and potential on the basis of submitted application material. No restrictions related to disabilities, citizenship or gender apply to ICFO positions. ICFO abides by the principles of openness, efficiency, transparency, supportiveness, and international comparability as stated in the European Charter for Researchers and the European Code of Conduct for the Recruitment of Researchers.

The contract is offered for periods of one year, renewable on an annual basis.

Application process

For informal inquiries please send a CV to Dr. Michael Tayler (michael.tayler@icfo.eu) and Prof. Morgan Mitchell (morgan.mitchell@icfo.eu)

The formal application should be submitted online via http://jobs.icfo.eu/index.php?detail=485

Suitable candidates are requested to submit:

Presentation letter with a declaration of interest,

Curriculum Vitae, including contact details,

Scanned copies of the complete (Bachelor and Master equivalent) official academic transcripts in English or Spanish,

The contact e-mail of two potential referees.

Candidates may contact jobs@icfo.eu for informal enquiries regarding the application, as well as address scientific enquiries to michael.tayler@icfo.eu

Deadline

Applications are considered on a continuing basis, until the positions are filled.

For updated information about ICFO, please visit http://www.icfo.eu/

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[NMR] POSTDOC(S) AT UC BERKELEY/CCNY #DNPNMR

POSTDOC(S) AT UC BERKELEY/CCNY

The research groups of Professors Alex Pines, Carlos Meriles, and Jeff Reimer have  funding for postdoctoral positions at UC Berkeley, in close collaboration with the City University of New York (CCNY). We are interested in nuclear hyperpolarization via  optical excitation in solids and MOFs with applications ranging from ranging from  fundamental many-body physics and quantum sensing to geochemistry and to  biomedicine. Most of the work would be done within the Pines and Reimer labs at  UC Berkeley, with some extended stays at the City University of New York. Compensation  is consistent with the union contract at UC Berkeley. The ideal candidate is able to  design, develop, and deploy new instrumentation; imagine models for spin physics;  and exhibit chemical intuition. Please send a cv to reimer@berkeley.edu

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[NMR] Post-doctoral position in CEA/Saclay

CEA, CNRS, Paris-Saclay University, France

A Postdoctoral research position is available from April 2020 to develop liquid-state NMR methods and instrumentation for sensitive real-time detection of synthesis intermediates. The efficient, rapid and quantitative detection of reaction intermediates by NMR requires that the detection zone be as close as possible to the synthesis reactor. This implies new developments in instrumentation and NMR methods.

The postdoctoral position is funded through an ANR project grant for a period of 12 months. Experience in two of the following areas is desirable: NMR methodology, NMR instrumentation, chemical engineering, 3D-printing. A benchtop NMR spectrometer (43 MHz), two 500 MHz narrow-bore spectrometers and a 300 MHz superwide-bore spectrometer/imager are available in the laboratory for this project. Also, the candidate will have access to the French high-field NMR facility (IR-RMN-THC).

CEA is a major French player in research, development and innovation. The Paris-Saclay cluster, situated 25 km in the south-west of Paris, is a concentration of large groups and innovative SMEs associated with a world-class university center. Being one of the 8 most important innovation centers in the world, Paris-Saclay already accounts for 15% of French public and private research.

Candidates who are interested in participating to this project common to the company CortecNet and the CEA (LSDRM) are encouraged to apply by sending their CV and letters of recommendation to Dr. Patrick Berthault, NIMBE, UMR CEA/CNRS 3685, CEA Saclay, PC #9, F-91191 Gif sur Yvette, France patrick.berthault@cea.fr.

More details on the developments at the origin of this project can be found in these refs:

[1] G. Carret, T. Berthelot, et P. Berthault, « Enhancing NMR of Nonrelaxing Species Using a Controlled Flow Motion and a Miniaturized Circuit », Anal. Chem., vol. 89, p. 2995‑3000, mars 2017. DOI: 10.1021/acs.analchem.6b04488

[2] G. Carret, T. Berthelot, et P. Berthault, « Inductive Coupling and Flow for Increased NMR Sensitivity », Anal. Chem., vol. 90, p. 11169‑11173, oct. 2018. DOI: 10.1021/acs.analchem.8b01775

Patrick Berthault

NIMBE, UMR CEA/CNRS 3685

CEA Saclay

PC #9

F-91191 Gif sur Yvette

France

Tel: +33 1 69 08 42 45

http://iramis.cea.fr/Pisp/patrick.berthault/

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[NMR] ERC-funded PhD positions in small-molecule NMR – Nantes, France #DNPNMR

Dear colleagues,

Three ERC-funded PhD positions are open in the Nantes NMR group of the CEISAM research institute, in the field of small-molecule NMR of complex mixtures.

The PhD students will join a dynamic NMR group and work on two ERC-funded projects led by Jean-Nicolas Dumez and Patrick Giraudeau. The three PhD projects will consist of:

1) developing methods for fast diffusion-ordered NMR spectroscopy (DOSY), based on the principles of spatial encoding (SPEN), for the monitoring of out-of-equilibrium systems. These methods will be applied to reaction monitoring on a variety of chemical systems.

2) developing ultrafast 2D NMR heteronuclear methods for the analysis of complex biological samples hyperpolarized by dissolution dynamic nuclear polarization. The methods will be applied to various research questions in the field of metabolomics.

3) developing a variety of homo- and hetero-nuclear NMR methods for the analysis of out-of-equilibrium complex mixtures involving flow analysis and/or hyperpolarization.

Applicants should have a background in chemistry (preferentially analytical or physical) or physics, and a strong interest in both fundamental and applied aspects of magnetic resonance.

The NMR group of the CEISAM lab works on method developments in solution-state NMR and their application to the analysis of mixtures. It is equipped with state-of-the-art NMR spectrometers, in the 400 to 700 MHz range, a microimaging system and a prototype polariser for dissolution-DNP. CEISAM is the molecular chemistry lab of the Université de Nantes, where research includes physical and analytical chemistry, organic synthesis and catalysis, and chemical biology. The lab is located in the vibrant city of Nantes, close to the Atlantic Coast of south Brittany.

Positions are for three years and will start on October 1st 2020. Please send applications including cover letter, CV and the name of two referees to Jean-Nicolas Dumez and Patrick Giraudeau. The first round of applications will be closed on March 31st.

Please forward this message to potential candidates.

Best regards

Jean-Nicolas Dumez and Patrick Giraudeau

Prof. Patrick GIRAUDEAU

CEISAM/Chemistry Department

Faculty of Science and Technology

Tel : (33)251125709

Mail: patrick.giraudeau@univ-nantes.fr

2 rue de la Houssinière BP 92208

44322 Nantes Cedex 3

FRANCE

Website: www.univ-nantes.fr/giraudeau-p

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Postdoctoral Position: EPR Spectroscopic Studies of Membrane Proteins #EPR

Postdoctoral Position: EPR Spectroscopic Studies of Membrane Proteins

Miami University, Oxford, OH, USA

A Postdoctoral research position is available immediately to study the structural and dynamic properties of integral membrane proteins in the laboratory of Prof. Gary A. Lorigan in the Department of Chemistry and Biochemistry at Miami University in Ohio. The postdoctoral position is funded through a NIH MIRA R35 grant.

Candidates who are interested in studying the structural and dynamic properties of membrane proteins are encouraged to apply. Experience in two of the following areas is desirable: molecular biology and biochemistry of membrane proteins, protein purification, and EPR spectroscopy. 2 pulsed EPR spectrometers (X-band/Q-band) for DEER and ESEEM experiments, 2 CW-EPR spectrometers, and a 500 MHz solid-state NMR instrument are available for this project. Miami University is home to the Ohio Advanced EPR Lab (http://epr.miamioh.edu). Please send a CV and two letters of recommendation to: Professor Gary A. Lorigan, Department of Chemistry and Biochemistry, Miami University gary.lorigan@miamioh.edu. A Ph.D. in Chemistry/Biochemistry or related fields is required. Contact phone is 513-529-3338. 

Miami University, an Equal Opportunity/Affirmative Action employer, encourages applications from minorities, women, protected veterans and individuals with disabilities. Miami University prohibits harassment, discrimination and retaliation on the basis of sex/gender (including sexual harassment, sexual violence, sexual misconduct, domestic violence, dating violence, or stalking), race, color, religion, national origin (ancestry), disability, age (40 years or older), sexual orientation, gender identity, pregnancy, status as a parent or foster parent, military status, or veteran status in its recruitment, selection, and employment practices. Requests for all reasonable accommodations for disabilities related to employment should be directed to ADAFacultyStaff@miamioh.edu or 513-529-3560.

As part of the University’s commitment to maintaining a healthy and safe living, learning, and working environment, we encourage you to read Miami University’s Annual Security & Fire Safety Report at http://www.MiamiOH.edu/campus-safety/annual-report/index.html(http://www.miamioh.edu/campus-safety/annual-report/index.html), which contains information about campus safety, crime statistics, and our drug and alcohol abuse and prevention program designed to prevent the unlawful possession, use, and distribution of drugs and alcohol on campus and at university events and activities. This report also contains information on programs and policies designed to prevent and address sexual violence, domestic violence, dating violence, and stalking. Each year, email notification of this website is made to all faculty, staff, and enrolled students. Written notification is also provided to prospective students and employees. Hard copies of the Annual Security & Fire Safety Report may be obtained from the Miami University Police Department at (513) 529-2225.

Gary A. Lorigan

John W. Steube Professor 

Department of Chemistry and Biochemistry

Miami University

651 E. High St.

Oxford, Ohio 45056

Office: 137 Hughes Laboratories

Phone: (513) 529-3338

Fax: (513) 529-5715

e-mail: gary.lorigan@miamioh.edu

web: www.users.muohio.edu/lorigag/index.html

EPR facility: epr.muohio.edu

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[NMR] Postdoctoral position \”DNP-enhanced biomolecular solid-state NMR\” #DNPNMR

Postdoctoral position \”DNP-enhanced biomolecular solid-state NMR-spectroscopy for the study of protein (mis)folding\”

A postdoctoral position is available in the group of Henrike Heise at Forschungszentrum Juelich/Heinrich Heine University Duesseldorf

The successful candidate will study disordered and aggregation-prone proteins in all stages of the misfolding pathway. Further, interaction with potential drug candidates will be elucidated. State-of-the art solid-state NMR-spectroscopy, involvng polarization enhancement by DNP and fast magic angle spinning will be applied to elucidate those processes at atomic resolution. A selection of relevant publication is given below.

Our laboratory at the Forschungszentrum Jülich is equipped with state of the art solid-state NMR spectrometers operating at 800 and 600 MHz, DNP equipment is available for 600 and 800 MHz spectrometers. An ultrafast MAS probe head for spinning speeds up to > 100 kHz will be available soon, the installation of an ultrahigh field spectrometer operating at 1.2 GHz is scheduled for 2020.

The Forschungszentrum Jülich offers a vibrant research environment with close collaborations with the University of Düsseldorf, the RWTH Aachen University and the Max-Planck Institute Mülheim. Our laboratory is part of the Jülich center of structural biology JuStruct which bundles expertise with infrastructure in the field of atomic resolution of structural biology (NMR in solution and the solid state, X-ray crystallography,cryo-EM, molecular modelling and neutron scattering).

The initial appointment is for a year, with a possibility of renewal.The initial appointment is for a year, with a possibility of renewal.

Applications will be reviewed on a rolling basis, and candidates will be considered until the position is filled.

The ideal candidate should have a strong background in biomolecular NMR-spectroscopy. Experience with hyperpolarization and/ or Protein expression and purfication is a plus. Applicants must submit a cover letter summarizing research experience and specifying the interests in this position; a curriculum vitae (including a publication list); a statement of research interests; and two letters of reference to henrike.heise@hhu.de

Information about our group:

http://www.fknmr.hhu.de/en/

Selection of relevant publications:

L. Siemons, B. Uluca-Yazgi, R. B. Pritchard, S. McCarthy, H. Heise, D. F. Hansen, Determining isoleucine side-chain rotamer-sampling in proteins from 13C chemical shift, Chem.Commun. 2019, in press. doi:10.1039/C9CC06496F.

A. König, D. Schölzel, B. Uluca, T. Viennet, Ü. Akbey, H. Heise, Hyperpolarized MAS NMR of unfolded and misfolded proteins, Solid State NMR, 2019, 98, 1-11.

B. Uluca, T. Viennet, D. Petrović, H. Shaykhalishahi, F. Weirich, A. Gönülalan, B. Strodel, M. Etzkorn, W. Hoyer, and H. Heise. DNP-Enhanced solid-state NMR at Cryogenic Temperatures: a Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States. Biophys. J. 2018, 114, 1614-1623.

L. Gremer, D. Schölzel, C. Schenk, E. Reinartz, J. Labahn, R. Ravelli, M. Tusche, C. Lopez-Iglesias, W. Hoyer, H. Heise, D. Willbold, G. Schröder, Fibril structure of amyloid-ß(1-42) by cryo-electron microscopy, Science, 2017, 358, 116-119.

T. Viennet, A. Viegas, A. Kuepper, S. Arens, V. Gelev, O. Petrov, T. N. Grossmann, H. Heise, M. Etzkorn, Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization. Angew. Chem. Int. Ed. Engl. 2016, 55, 10746-10750.

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Forschungszentrum Juelich GmbH

52425 Juelich

Sitz der Gesellschaft: Juelich

Eingetragen im Handelsregister des Amtsgerichts Dueren Nr. HR B 3498

Vorsitzender des Aufsichtsrats: MinDir Volker Rieke

Geschaeftsfuehrung: Prof. Dr.-Ing. Wolfgang Marquardt (Vorsitzender),

Karsten Beneke (stellv. Vorsitzender), Prof. Dr.-Ing. Harald Bolt,

Prof. Dr. Sebastian M. Schmidt

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[NMR] Postdoctoral Positions in Solid-State NMR and DNP to Investigate Biomolecules and Biomaterials #DNPNMR

Postdoctoral Positions in Solid-State NMR and DNP to Investigate Biomolecules and Biomaterials @ Louisiana State University

We are looking for two motivated postdoctoral researchers. Preferences will be given to candidates with prior experience in NMR spectroscopy (biomolecular or material NMR) and/or relevant directions such as structural biology, modeling, and programming. Expertise in solid-state NMR is preferred by not required.

The earliest starting dates for both positions are Jan 01, 2020. Please send applications to Tuo Wang (tuowang@lsu.edu) with a CV and the names and contact information for three individuals willing to provide professional letters of support. Please do not hesitate to contact us if you have any questions.​

Wang research group currently has a postdoctoral researcher and five graduate students working on a large variety of solid-state NMR and DNP projects to elucidate the structure and dynamics of carbohydrates, proteins, and other biopolymers in cellular context, the structural characterization of membrane proteins, and the development of a carbohydrate database. 

The LSU campus is located in Baton Rouge, the capital of Louisiana, and is one of the most beautiful campuses in the US. I believe you will have a joyful and fruitful journey at LSU.

Tuo Wang

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Tuo Wang

Assistant Professor

Department of Chemistry

Louisiana State University

329 Choppin Hall

Baton Rouge, LA, 70803

Tel: 225-578-3922

https://sites01.lsu.edu/faculty/tuowang/

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[NMR] Postdoc: Solid-state NMR at 1.2 GHz

Postdoc position at ETH Zurich:

for the development of fast MAS methods and biomolecular applications at high field (in particular at 1.2 GHz) in the group of Beat Meier (http://nmr.ethz.ch), we look for a postdoctoral researcher with a strong experimental background in solid-state NMR. Experience with NMR hardware and with biomolecular applications and structural biology is an asset. Spectrometers at 600 and 850 MHz are available and a 1.2 GHz system is expected in the first half of 2020.

The position is available from January 1, 2020 (or later) and is initially planned for for 1 year (renewable). Candidates should send a CV and the names of at least two references to Beat Meier (beme@ethz.ch)

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[NMR] Postdoc: Solid-state NMR at 1.2 GHz

Postdoc position at ETH Zurich: for the development of fast MAS methods and biomolecular applications at high field (in particular at 1.2 GHz) in the group of Beat Meier (http://nmr.ethz.ch), we look for a postdoctoral researcher with a strong experimental background in solid-state NMR. Experience with NMR hardware and with biomolecular applications and structural biology is an asset. Spectrometers at 600 and 850 MHz are available and a 1.2 GHz system is expected in the first half of 2020.

The position is available from January 1, 2020 (or later) and is initially planned for for 1 year (renewable). Candidates should send a CV and the names of at least two references to Beat Meier (beme@ethz.ch)

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Postdoctoral position: DNP-enhanced biomolecular solid-state NMR-spectroscopy for the study of protein (mis)folding #DNPNMR

A postdoctoral position is available in the group of Henrike Heise at Forschungszentrum Juelich/Heinrich Heine University Duesseldorf

The successful candidate will study disordered and aggregation-prone proteins in all stages of the misfolding pathway. Further, interaction with potential drug candidates will be elucidated. State-of-the art solid-state NMR-spectroscopy, involvng polarization enhancement by DNP and fast magic angle spinning will be applied to elucidate those processes at atomic resolution. A selection of relevant publication is given below.

Our laboratory at the Forschungszentrum Jülich is equipped with state of the art solid-state NMR spectrometers operating at 800 and 600 MHz, DNP equipment is available for 600 and 800 MHz spectrometers. An ultrafast MAS probe head for spinning speeds up to > 100 kHz will be available soon, the installation of an ultrahigh field spectrometer operating at 1.2 GHz is scheduled for 2020.

The Forschungszentrum Jülich offers a vibrant research environment with close collaborations with the University of Düsseldorf, the RWTH Aachen University and the Max-Planck Institute Mülheim. Our laboratory is part of the Jülich center of structural biology JuStruct which bundles expertise with infrastructure in the field of atomic resolution of structural biology (NMR in solution and the solid state, X-ray crystallography,cryo-EM, molecular modelling and neutron scattering).

The initial appointment is for a year, with a possibility of renewal.The initial appointment is for a year, with a possibility of renewal.

Applications will be reviewed on a rolling basis, and candidates will be considered until the position is filled.

The ideal candidate should have a strong background in biomolecular NMR-spectroscopy. Experience with hyperpolarization and/ or Protein expression and purfication is a plus. Applicants must submit a cover letter summarizing research experience and specifying the interests in this position; a curriculum vitae (including a publication list); a statement of research interests; and two letters of reference to henrike.heise@hhu.de

Information about our group:

http://www.fknmr.hhu.de/en/

Selection of relevant publications:

  • L. Siemons, B. Uluca-Yazgi, R. B. Pritchard, S. McCarthy, H. Heise, D. F. Hansen, Determining isoleucine side-chain rotamer-sampling in proteins from 13C chemical shift, Chem.Commun. 2019, in press. doi:10.1039/C9CC06496F.
  • A. König, D. Schölzel, B. Uluca, T. Viennet, Ü. Akbey, H. Heise, Hyperpolarized MAS NMR of unfolded and misfolded proteins, Solid State NMR, 2019, 98, 1-11.
  • B. Uluca, T. Viennet, D. Petrović, H. Shaykhalishahi, F. Weirich, A. Gönülalan, B. Strodel, M. Etzkorn, W. Hoyer, and H. Heise. DNP-Enhanced solid-state NMR at Cryogenic Temperatures: a Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States. Biophys. J. 2018, 114, 1614-1623.
  • L. Gremer, D. Schölzel, C. Schenk, E. Reinartz, J. Labahn, R. Ravelli, M. Tusche, C. Lopez-Iglesias, W. Hoyer, H. Heise, D. Willbold, G. Schröder, Fibril structure of amyloid-ß(1-42) by cryo-electron microscopy, Science, 2017, 358, 116-119.
  • T. Viennet, A. Viegas, A. Kuepper, S. Arens, V. Gelev, O. Petrov, T. N. Grossmann, H. Heise, M. Etzkorn, Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization. Angew. Chem. Int. Ed. Engl. 2016, 55, 10746-10750.

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————————————————————————————————

Forschungszentrum Juelich GmbH

52425 Juelich

Sitz der Gesellschaft: Juelich

Eingetragen im Handelsregister des Amtsgerichts Dueren Nr. HR B 3498

Vorsitzender des Aufsichtsrats: MinDir Volker Rieke

Geschaeftsfuehrung: Prof. Dr.-Ing. Wolfgang Marquardt (Vorsitzender),

Karsten Beneke (stellv. Vorsitzender), Prof. Dr.-Ing. Harald Bolt,

Prof. Dr. Sebastian M. Schmidt

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